30 day Money Back GuaranteeWhy does ORAVIA Harmony45+ Spray work better?
Based on feedback from 174 real women*
Harmony45+ Spray is the only supplement of its kind offering a 2-phase approach to menopause:
Instant Harmony Technology™ — Immediate relief from the most disruptive symptoms
Oravia Harmony45+ uses a unique spray-based formula for absorption directly through the oral mucosa. That means active ingredients go straight into your bloodstream and start working right away — no waiting for digestion, no wasted ingredients.
✔️ Noticeable effects within 1–2 minutes
✔️ Absorption up to 4x more effective than capsules or tablets
✔️ No drowsiness, no “crash”, no unwanted weight gain
Mind & Body Balance Complex™ — Whole-person support for mood, sleep, and daily wellbeing
Harmony45+ was developed to offer not just fast symptom relief, but genuine, holistic support for women’s physical and emotional needs. The combination of five powerful ingredients works on multiple levels to restore calm, reduce heat and tension, and support a brighter mood day after day.
The key are five ingredients with synergistic effects, confirmed in clinical studies:
Vitamin B6 (pyridoxine HCl)
A vital B vitamin that helps regulate hormonal activity, stabilize mood, and support healthy nervous system function—crucial for women facing mood swings, irritability, and fatigue during menopause.
Its role in neurotransmitter synthesis and hormone modulation helps reduce both emotional and physical symptoms, promoting a greater sense of balance and wellbeing.
➡️ A scientific opinion from the European Food Safety Authority (EFSA) confirms that daily supplementation with vitamin B6 contributes to the regulation of hormonal activity and normal nervous system function in adult women.
L-Theanine (β-cyclodextrin complex)
A natural amino acid from green tea, uniquely formulated for rapid absorption, that promotes calmness and relaxation without sedation.
By supporting GABA and serotonin pathways, L-theanine helps reduce stress, anxiety, and the “heat-triggered” irritability that are so common during menopause—restoring emotional stability within minutes.
➡️ A clinical study demonstrated that a single dose of L-theanine significantly reduced stress responses, lowered heart rate, and improved subjective feelings of calm in adults exposed to psychological stress.
Affron® (saffron extract ≥ 3.5% crocins)
A premium, standardized saffron extract clinically shown to modulate neurotransmitter levels, lift mood, and relieve irritability or emotional lows during menopause.
Its unique crocin content supports emotional balance and has been proven to improve both psychological and physical symptoms in perimenopausal and menopausal women.
➡️ Randomized clinical trials and meta-analyses show that saffron supplementation significantly reduces symptoms of depression, anxiety, and emotional instability, with effects confirmed in women experiencing menopausal symptoms.
Lopresti et al., 2019 – Saffron for depression and anxiety: meta-analysis
High-Menthol Blend (menthol + eucalyptol)
An advanced blend that instantly activates cold-sensitive TRPM8 receptors, delivering an “arctic blast” of cooling under the tongue and retronasally—providing rapid relief from hot flashes, heat surges, and night sweats.
The cooling effect not only interrupts the sensation of heat, but also improves thermal comfort and helps you regain control during sudden episodes.
➡️ Peer-reviewed research confirms that menthol rapidly stimulates cold receptors, creating a pronounced and sustained cooling sensation that reduces perceived heat and improves comfort.
Eccles, 1994 – Menthol and cooling compounds: mechanism and effect
Patel et al., 2017 – Menthol-induced cooling for skin comfort
BioPerine® (piperine)
A patented black pepper extract that dramatically boosts the bioavailability of all other actives, ensuring you get the full benefit from each dose.
Piperine works by enhancing nutrient absorption and protecting plant compounds from breakdown, making the formula faster-acting and more effective.
➡️ Clinical studies have shown that piperine can increase the bioavailability of nutrients (like curcumin, vitamins, and herbal extracts) by up to 30%, supporting stronger and more consistent effects.
Shoba et al., 1998 – Piperine boosts nutrient absorption in humans
Badmaev et al., 2000 – Review: Piperine increases nutrient bioavailability
Why women love Oravia Harmony45+ Spray
✔️ Noticeable effects in just 1–2 minutes — wherever you are
✔️ Hormone-free and non-addictive — perfect for women who want natural, safe options
✔️ No prescription required — available directly, no doctor visit needed
✔️ No side effects — doesn’t cause weight gain, grogginess, or menstrual changes
✔️ Elegant, discreet, and easy to use — just one spray for fast support
When will you feel the difference?
📅 1–2 minutes — first signs of calm, cooling, and relief from heat and mood swings
📅 Day 3–5 — more stable emotions, better sleep, fewer unpredictable hot flashes
📅 Week 2+ — improved daily wellbeing, restored confidence, “more like yourself again”
📅 Month 1+ — steady, long-lasting balance and comfort, with no drop-off in effectiveness
Composition (in 3 sprays):
Comparison
How to use it?
- Spray once under the tongue at the first sign of hot flash, mood swing, or night-time discomfort
- Hold for 30 seconds, then swallow
- May repeat up to 3x per day as needed
- Works anytime, even on an empty stomach
Satisfaction guarantee
At Oravia, we understand how disruptive menopause can be — because we listen to real women every day. That’s why we offer a 60-day satisfaction guarantee on Harmony45+ Spray. If you don’t notice a real difference, just let us know — even if you’ve used the product — and we’ll refund your purchase, no questions asked. You deserve to feel your best.
Frequently Asked Questions about ORAVIA Harmony45+ Spray
ORAVIA Harmony45+ Spray is designed for women experiencing perimenopause or menopause symptoms, such as hot flashes, mood swings, night sweats, irritability, anxiety, or poor sleep. It’s ideal for those seeking a fast, hormone-free, and convenient solution for symptom relief.
You’ll typically feel noticeable relief within 1–2 minutes of spraying under the tongue, thanks to rapid sublingual absorption. Simply use 1–2 sprays at the onset of symptoms (hot flash, anxiety, irritability, etc.), hold under your tongue for 30 seconds, then swallow. You can repeat up to 3 times per day as needed.
Yes. Harmony45+ is hormone-free and is generally safe to use alongside HRT or other menopause supplements. However, if you take prescription medications or have health concerns, consult your healthcare provider before starting any new supplement.
ORAVIA Harmony45+ Spray is formulated to be well-tolerated and does not cause weight gain, drowsiness, or changes in menstrual cycles. Rarely, people sensitive to menthol or pepper may notice a mild tingling sensation. If you have allergies or a medical condition, check the ingredient list and consult your doctor.
Yes, many women find that Harmony45+ Spray helps them sleep better and wake up less often due to night sweats. The calming blend of L-theanine and saffron also supports mood and relaxation at night.
Yes. The formula is completely hormone-free and does not contain estrogen or phytoestrogens. It can be used by women who cannot or prefer not to use HRT, including those after breast cancer (but always consult your doctor if you have a medical history).
One bottle typically lasts 30–45 days with regular daily use. Store it at room temperature, away from direct sunlight and heat. Make sure to close the cap tightly after each use.
Yes, it has a fresh, cooling mint and herbal flavor with a subtle peppery note, designed to feel pleasant and refreshing during hot flashes.
Yes. The spray is suitable for vegans and vegetarians. It is free from common allergens such as gluten, soy, lactose, and artificial flavors. See the full ingredient list to check for any personal sensitivities.
No. ORAVIA Harmony45+ Spray is cruelty-free and is not tested on animals.
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